Betsy Mitchell has been a New York science fiction/fantasy editor for more than 30 years, holding senior positions at Baen, Bantam Spectra, Warner Books, and the Random House Publishing Group, where she spent ten years as Vice President/Editor-in-Chief of Del Rey. She currently runs her own editing business, Betsy Mitchell Editorial Services, and is building a genre list at digital publisher Open Road Integrated Media.

She has edited more than 150 titles, including such works as Gentlemen of the Road by Michael Chabon, Bearers of the Black Staff by Terry Brooks, Virtual Light by William Gibson, and Empire of Ivory by Naomi Novik (all New York Times bestsellers); the Hugo Award-winner Hyperion by Dan Simmons, and the Nebula Award-winner Parable of the Talents by Octavia Butler. She received a World Fantasy Award for co-editing the anthology Full Spectrum 4.

In May 2004 she oversaw the launch of Del Rey Manga and went on to edit a number of graphic novels, including the #1 New York Times bestsellers The Exile by Diana Gabaldon, Odd is on Our Side by Dean Koontz and Fred van Lente, and Blood Work by Kim Harrison.